Sickle cell disease is a disorder in which blood cells carry a mutation in hemoglobin. 镰状细胞贫血病是由于血细胞携带了一种突变的血红蛋白导致的紊乱。
People with sickle cell disease have a faulty gene that makes their red blood cells change shape and block small blood vessels. 患有镰状细胞病的人拥有一个缺陷基因,这让他们的红细胞改变形状,阻塞小血管。这会导致疼痛、器官损伤和中风。
In one particular inherited disease, sickle cell anaemia, the red blood cells, instead of being flat discs, are sickle shaped. 在一种特殊的遗传疾病镰形细胞贫血症中,红血球不是圆盘状而是镰刀状。